Peer Reviewed Publications:

  1. Rendon CJ, Sempere L, Lauver A, Watts SW, Contreras GA. Anatomical Location, Sex, and Age Modulate Adipocyte Progenitor Populations in Perivascular Adipose Tissues. Front Physiol. 2024. Accepted.

  2. Sadko KJ, Leishman DJ, Bailie MB, Lauver DA. A simple accurate method for concentration-QTc analysis in preclinical animal models. J Pharmacol Toxicol Methods. 2024 Jun 7;128:107528. doi: 10.1016/j.vascn.2024.107528. Epub ahead of print. PMID: 38852684.

  3. Wilson C, Thompson JM, Terrian L, Lauver AD, Flood ED, Fink GD, Sather L, Bhattacharya S, Contreras GA, Watts SW. Perivascular Adipose Tissue Remodels Only after Elevation of Blood Pressure in the Dahl SS Rat Fed a High-Fat Diet. J Vasc Res. 2024;61(1):26-37. doi: 10.1159/000535513. Epub 2023 Dec 19. PMID: 38113863; PMCID: PMC10836923.

  4. Volmert B, Kiselev A, Juhong A, Wang F, Riggs A, Kostina A, O'Hern C, Muniyandi P, Wasserman A, Huang A, Lewis-Israeli Y, Panda V, Bhattacharya S, Lauver A, Park S, Qiu Z, Zhou C, Aguirre A. A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization. Nat Commun. 2023 Dec 12;14(1):8245. doi: 10.1038/s41467-023-43999-1. PMID: 38086920.

  5. Leishman DJ, Holdsworth DL, Lauver DA, Bailie MB, Roche BM. The "One-Step" approach for QT analysis increases the sensitivity of nonclinical QTc analysis. Clin Transl Sci. 2023 Nov;16(11):2253-2264. doi: 10.1111/cts.13625. Epub 2023 Sep 19. PMID: 37726963.

  6. Kuszynski DS, Christian BD, Bernard MP, Lauver DA. Evaluation of the Efficacy and Safety of Antiplatelet Therapeutics in Rabbits. Curr Protoc. 2023 Mar;3(3):e711. doi: 10.1002/cpz1.711. PMID: 36921209.

  7. Ether ND, Leishman DJ, Bailie MB, Lauver DA. QT Ratio: A simple solution to individual QT correction. J Pharmacol Toxicol Methods. 2022 Sep-Oct;117:107211. doi: 10.1016/j.vascn.2022.107211. Epub 2022 Aug 22. PMID: 36007862.

  8. Kuszynski DS, Lauver DA. Pleiotropic effects of clopidogrel. Purinergic Signal. 2022 Sep;18(3):253-265. doi: 10.1007/s11302-022-09876-0. Epub 2022 Jun 9. PMID: 35678974; PMCID: PMC9391547.

  9. Ether ND, Jantre SR, Sharma DB, Leishman DJ, Bailie MB, Lauver DA. Improving corrected QT; Why individual correction is not enough. J Pharmacol Toxicol Methods. 2022 Jan-Feb;113:107126. doi: 10.1016/j.vascn.2021.107126. Epub 2021 Oct 13. PMID: 34655760.

  10. Kuszynski DS, Christian BD, Dorrance AM, Lauver DA. Clopidogrel treatment inhibits P2Y2-Mediated constriction in the rabbit middle cerebral artery. Eur J Pharmacol. 2021 Nov 15;911:174545. doi: 10.1016/j.ejphar.2021.174545. Epub 2021 Oct 2. PMID: 34606835; PMCID: PMC8577565.

  11. Ether N, Leishman D, Bailie M, Lauver A. Relationship of clinical adverse event reports to models of arrhythmia risk. J Pharmacol Toxicol Methods. 2019 Nov-Dec;100:106622. doi: 10.1016/j.vascn.2019.106622. Epub 2019 Aug 6. PMID: 31398384.

  12. Lauver DA*, Kuszynski DS, Christian BD, Bernard MP, Teuber JP, Markham BE, Chen YE, Zhang H. DT-678 Inhibits Platelet Activation with Lower Tendency for Bleeding Compared to Existing P2Y12 Antagonists. Pharmacology Research and Perspectives. 2019 Jul 25;7(4):e00509. PMCID: PMC6658415 *Corresponding author

  13. Gurm HS, Seth M, Dixon SR, Grossman PM, Sukul D, Lalonde T, Cannon L, West D, Madder RD, Lauver DA. Contemporary use of and outcomes associated with ultra-low contrast volume in patients undergoing percutaneous coronary interventions. Catheter Cardiovasc Interv. 2019 Feb 1;93(2):222-230. doi: 10.1002/ccd.27819. Epub 2018 Aug 25. PMID: 30144337.

  14. Zhang H, Lauver DA, Wang H, Sun D, Hollenberg PF, Chen YE, Osawa Y, Eitzman DT. Significant Improvement of Antithrombotic Responses to Clopidogrel by Use of a Novel Conjugate as Revealed in an Arterial Model of Thrombosis. The Journal of Pharmacology and Experimental Therapeutics. 2016 Oct;359(1):11-7.

  15. Lauver DA*, Carey EG, Bergin IL, Lucchesi BR, Gurm HS. Sildenafil citrate for prophylaxis of nephropathy in an animal model of contrast-induced acute kidney injury. PLoS One. 2014 Nov 26;9(11):e113598. *Corresponding author

  16. Zhang H, Lauver DA, Hollenberg PF. CYP-independent inhibition of platelet aggregation in rabbits by a mixed disulfide conjugate of clopidogrel. Thrombosis and Haemostasis. 2014 Dec 1;112(6):1304-11.

  17. Zhang H, Lauver DA, Lucchesi BR, Hollenberg PF. Formation, reactivity, and antiplatelet activity of mixed disulfide conjugates of clopidogrel. Molecular Pharmacology. April 2013; 83(4):848-856.

  18. Lauver DA, Kaissarian NM, Lucchesi BR. Oral pretreatment with liposomal glutathione attenuates reperfusion injury in rabbit isolated hearts. Journal of Cardiovascular Pharmacology. Mar 2013; 61(3):233-239.

  19. Lauver DA*, Rimon G*, Sidhu RS*, Lee JY, Sharma NP, Yuan C, Frieler RA, Trievel RC, Lucchesi BR, Smith WL. Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1. Proceedings of the National Academy of Science. Jan 5 2010;107(1):28-33. * D.A.L., G.R., and R.S.S., contributed equally to this work.

  20. Lauver DA, Driscoll EM, Lucchesi BR. Disodium disuccinate astaxanthin prevents carotid artery rethrombosis and ex vivo platelet activation. Pharmacology. 2008;82(1):67-73. doi: 10.1159/000132085. Epub 2008 May 14. PMID: 18477858.

  21. Lauver DA, Lucchesi BR. Sulodexide: a renewed interest in this glycosaminoglycan. Cardiovasc Drug Rev. 2006 Fall-Winter;24(3-4):214-26. doi: 10.1111/j.1527-3466.2006.00214.x. PMID: 17214598.

  22. Lauver DA, Lockwood SF, Lucchesi BR. Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. J Pharmacol Exp Ther. 2005 Aug;314(2):686-92. doi: 10.1124/jpet.105.087114. Epub 2005 May 4. PMID: 15872041.

  23. Lauver DA, Booth EA, White AJ, Poradosu E, Lucchesi BR. Sulodexide attenuates myocardial ischemia/reperfusion injury and the deposition of C-reactive protein in areas of infarction without affecting hemostasis. J Pharmacol Exp Ther. 2005 Feb;312(2):794-800. doi: 10.1124/jpet.104.075283. Epub 2004 Sep 13. PMID: 15365091.

  24. Wang X, Dorsam RT, Lauver A, Wang H, Barbera FA, Gibbs S, Varon D, Savion N, Friedman SM, Feuerstein GZ. Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion. J Pharmacol Exp Ther. 2002 Dec;303(3):1114-20. doi: 10.1124/jpet.102.038513. PMID: 12438534.

Non-Peer Reviewed Publications

  1. Lauver DA. Remembering Dr. Benedict Robert Lucchesi (1933-2020). The Pharmacologist. Sept 2020;62(3):164-166.

D. Adam Lauver, PhD  |  lauverda@msu.edu  |  1355 Bogue Street, B336 Life Science Building, East Lansing, MI 48824